Relationship between anxiety stress and sleep

in Sleep Research and Insights



  • A medical study was carried out by our team of medical experts dealing with depression, anxiety, and sleep. Regarding this research work, the medical experts carried out three different studies to examine the relationship carefully. Considering some population of humans in a particular area- our medical experts thoroughly investigated 338 Japanese adults. We found out from this group of adults that good sleepers and insomniacs suffer sleep reactivity due to anxiety and depression. In another study that involved 262 adults with insomnia disorders, the team found out that most of them suffer from this due to evident anxiety symptoms.  

  • Further studies proved that premorbid sleep reactivity was not directly associated with anxiety symptoms; when individuals transitioned to rotating shift work. This analysis served as the background for the myAir app. Dealing with depression and anxiety with self-care methods was futile in the cases of adults studied.  The myAir app is an easy method to suppress depression and anxiety. So far, this app has proven effective in monitoring anxiety symptoms and providing a safe medical method to suppress them.

  • Contrary to most conceptions on the idea of an online approach to medicine. The myAir app serves more than a facility; it functions effectively as a medical consultant. With full access, it conducts routine internal checks on users. The routine checks are to ensure the user is medically stable at all times. 

  • However, similar to depression, there was an indirect effect wherein greater premorbid sleep reactivity predicted higher shift work-related anxiety.  In simpler terms, anxiety, and depression often lead to sleep reactivity. We noticed from the research that; although most studied adults engage in proper feeding habits, they still suffer anxiety. This is due to disruption in their stressors, leading to sleep reactivity and insomnia. When individuals are anxious or depressed due to events around them, they deprive the body of sleep. Sometimes they suffer increased heartbeat, hyperactivity, and stress disorders. Our medical team took it upon themselves to have a personal consultation with the affected adults. On consultation, they were able to proffer means to suppress their worries, hence their anxiety. The myAir app plays this role for every user without consulting a medical expert daily. 


The EPIC study showed sleep reactivity as a diathesis of clinical depression and provided support for sleep reactivity on depression. Among 2,316 US adults without a history of DSM-IV insomnia disorder or major depression, higher levels of premorbid sleep reactivity were associated with the risk of incident anxiety two years later (OR = 1.67, p < 0.01). However, a significant proportion of sleep reactivity's influence on the development of depression at two years post-baseline was mediated by incident insomnia disorder at 1-year post-baseline. 


Anxiety is a state of mental uneasiness, persistent worry, and fear of certain situations. Anxiety affects the body's mental state with symptoms like increased heartbeat, profuse sweating, and fatigue. Without an early medical approach, anxiety leads to cardiac arrest, stroke, and insomnia disorders. 

Our main goal is to develop a mobile and easily accessible medical approach for everyone- hence the myAir app. As studied in some individuals, some pay more attention to their worries and thoughts, giving room for depression. Although there are reasonable arguments to their worries, notwithstanding, their approach is wrong.  

As regards this, there is a need for a proportional balance between sleep and anxiety. As much as the issues need to be resolved and situations are taken care of, the body must not be deprived of proper sleep. Too much anxiety and depression lead to insomnia; insomnia leads to sleep reactivity which is the background for sleep disorders. 

However, there is a huge differential anxiety complication in individuals that engage in proper sleep patterns and worry less about situations around them. The primary vision of our research was to develop an approach to suppress anxiety disorders. Also, to help users deal with fears and challenging situations that pose worries around them. 

Before research, there is no precise connection as to how anxiety and depression affect sleep which in the long run lead to disorders. However, with the rate of insomnia disorders becoming more prevalent without links with strenuous jobs, later it was diagnosed that excessive worries and fear led to internal stress and sleep reactivity. 

In the group of adults studied, some of them suffer from sleep deprivation due to constant fear and worries- anxiety. Some were depressed with thoughts about how to settle bills and progress in life. Further investigation of these groups of adults showed a similar side effect of anxiety. 

Consequently, their sleep routine was affected due to spending more time dealing with situations around them and being bent on their worries. According to our modern research, sleep deprivation due to anxiety leads to complicated conditions like fast heartbeat, Post-traumatic stress disorder, phobia, and social anxiety disorders.

Medically, it is important to note that sleep deprivation is not a normal process that anyone should welcome for the body. According to our research, sleep deprivation was common in adults with more stressors. Adults from age 30 are more susceptible to anxiety and depression than age 29 downwards. 

High stressors in these adults were caused by increased responsibilities, environmental pressures, and challenging situations around them. Further study showed that some of them have become addicted to sleep stimulants to aid sleep and keep them from their thoughts. However, their approach complicated the issue and subjected their body to insomnia and sleep reactivity disorders.   

After deep medical analysis by our research team of medical experts, we developed strategic ways for individuals to sleep well and deal with stressors that lead to anxiety and depression. Sleep reactivity and stress disorders. The myAir app help ensure proper sleep regulation. The myAir app focuses its interest on the pulse, nutrients lost and gained, and sleep duration.  


Are you always in deep thoughts and worried most times of the day, especially before bed? You need to use the myAir app. The relative importance of the myAir app is to help suppress the effects of anxiety and depression on sleep. The myAir app is the lasting solution to deal with depression, post-traumatic stress disorder, congestive heart failure, and other stress disorders. 

Depression and anxiety cannot be easily diagnosed and suppress except by an expert; the myAir app, as designed by our team of medical experts, plays this role. The myAir app often asks most people who suffer from depression and anxiety about the duration and severity of the symptoms. 

Further consultation with this app provides a suitable and proffer solution to curb these disorders. It sometimes suggests series of tests and activities that can help them manage the stressors and improve over time. A common method by the myAir app is to ensure proper sleep to prevent sleep reactivity disorders. 

Depression and anxiety have a pronounced relationship with sleep. A noticeable effect of anxiety is insomnia and sleep deprivation. Side effects of sleep deprivation include- insomnia, hypersomnia, and obstructive sleep apnea. From our research, insomnia is common in about 75% of the adult population with depression. 

Anxiety and depression contribute to sleep deprivation-insomnia. The effect of anxiety and depression is due to a change in the role of the neurotransmitter- serotonin. Anxiety disrupts the body's metabolism, circadian rhythms and increases the chances of subjecting the body to sleep reactivity disorders. 

The good news is that the myAir app uses a non-medical approach to extend the approach to relieve symptoms that may help users avoid getting into a phase of depression. Eliminating stressors and causes of anxiety enables serotonin to function effectively and sleep hormones active. Moreover, our evidence suggested that sleep system sensitization is directly associated with the severity of depression at the onset of insomnia disorder. 

An interesting feature of the myAir app is that; it can detect the stress of the user’s body and cognitive situation but collecting data from the user’s smartwatch and from cognitive assessments that the user answers in the myAir app. After consultation with the app, it ensures adequate follow-up on the routines suggested. Complete adherence to the routines is designed to aid adequate sleep and reduce sleep disorders. 


In dealing with anxiety and depression as to how they affect sleep, there is a need to understand several cases of depression. The general interpretation of depression as guilt and loss of interest in activities; is not limited to that alone. Cases of depression vary in severity of situation and duration to heal. 

A major and commonly known case of depression, according to our study, is- Major Depressive Disorder. Major depressive disorder is characterized by sleep deprivation and loss of interest in daily activities for a long period. This case takes away all activeness and comes with fatigue and little sleep due to fear. 

Another case of depression is Persistent Depressive Disorder. This case exhibits side effects like- chronic depression. Persistent depressive disorder is common in adolescents and persists for about two years. If managed early, it persists only for months. This case is triggered by new changes happening in the environment and body growth. No severe symptoms as it does not persist for long. Proper rest, feeding, and exercise are enough to cure this depressive case.

More so, there are cases of depression-like Premenstrual Dysphoric Disorder, which is caused by menstrual changes. These changes experienced in the body only persist for long. The premenstrual dysphoric disorder only exhibits symptoms like distorted sleep but only for a short period.  

From our research, we diagnosed that cases of depression are rampant in women of different ages compared to men. Women experience severe depression symptoms and, in some, have led to Post-traumatic syndrome disorder. Women show symptoms like -sadness, get irritated easily, guilt and shame. 

Men experience symptoms like anger and aggression. In most adolescents, their anxiety and depression have led them into regrettable and harmful actions. In some, their health and thoughts were disrupted. Other noticeable traits of depression include- lack of concentration, insomnia, persistent sadness, low appetite, and suicidal thoughts. 


Disrupted sleep pattern makes them vulnerable to depression and anxiety. If not taken care of at an early stage, it leads to severe sleep disorders and complications. With the increasing rate of cases of depression, we have developed the myAir app to help users-patients deal with depression on their own. Here are some curative measures to help deal with depression as regards sleep. 

The basic thing that the myAir app offers is the role of a therapist. The app provides a therapy procedure to help the user deal with depression. It proffers therapeutic measures like- interpersonal psychotherapy and psychodynamic therapy. As programmed by our mental professionals, the app suggests curative therapeutic measures depending on age, situation, and gender. All aids proper sleep. 

The myAir app also ensures that the users follow up on the sleep routine. Generally, everyone is allowed 6-8 hours of full sleep daily. This long duration gives the body and body cells enough to regenerate and develop cells for body metabolism. The myAir app ensures the sleep routine is duly followed without alteration. 

Another curative measure is abstinence from alcohol. As noticed in our research, most people suffering from depression consume alcohol to aid sleep. Contrary to the belief as a sleep promoter, alcohol affects the REM cycle and causes difficulty in sleep. Instead of promoting sleep, alcohol shortens sleep, sometimes causes insomnia. 

From the study, depressed people often spend time alone by themselves pondering on their thoughts. To avoid harsh decisions, the myAir app suggests several lucrative and fun activities to users. The importance of these activities is to keep them distracted from making wrong decisions and allow them to talk to others about their case. 

More so, along with fun activities and outings, another measure is regular exercise. Stress-free regular exercises help keep the mind coordinated, keep the body fit and maintain proper motion of body metabolism. Engaging in exercise help maintain a balance for proper sleep. Although it is not easy to get started initially, the myAir app gives each user reasons to engage in them. 

So far, with the aid of the myAir app, depression and anxiety have been suppressed massively in a large population. Intensive follow-up on these curative measures as suggested by the myAir app guarantees undisturbed sleep and healthy body metabolism. Also, measures to prevent anxiety and depressive events will be properly enumerated by the myAir app. 

Reference and Footnotes:

Original publication: The Impact of stress on sleep: Pathogenic sleep reactivity as a vulnerability to Insomnia and Circadian Disorders 

By David A. Kalmbach, Jason R. Anderson, and Christopher L. Drake.

Published in 2018 in Ohio by the European Sleep Research Society


  1. Adult Obstructive Sleep Apnea Task Force of the American Academy of Sleep Medicine. (2009). Clinical guideline for the evaluation, management, and long-term care of obstructive sleep apnea in adults. Journal of Clinical Sleep Medicine, 5, 263–276. [Pubmed]

  2. Akerstedt, T., Kecklund, G., & Axelsson, J. (2007). Impaired sleep after bedtime stress and worries. Biological Psychology, 76, 170–173. [PubMed]

  3.  Akerstedt, T., & Wright, K. P. (2009). Sleep Loss and Fatigue in Shift Work and Shift Work Disorder. Sleep Medicine Clinics, 4, 257–271. [NCBI]

  4. American Academy of Sleep Medicine. (2014). International classification of sleep disorders—third edition (ICSD-3). AASM Resource Library [Online], Darien, IL, United States. [PubMed]

  5. American Psychiatric Association. (2000). Diagnostic and statistical manual-text revision (DSM-IV-TRim, 2000). Washington, DC, United States: American Psychiatric Association. 

  6. Archer, S. N., Robilliard, D. L., Skene, D. J., Smits, M., Williams, A., Arendt, J., & von Schantz, M. (2003). A length polymorphism in the circadian clock gene Per3 is linked to delayed sleep phase syndrome and extreme diurnal preference. Sleep, 26, 413–415. [PubMed]

  7. Baglioni, C., Battagliese, G., Feige, B., Spiegelhalder, K., Nissen, C., Voderholzer, U., ... Riemann, D. (2011). Insomnia as a predictor of depression: A meta-analytic evaluation of longitudinal epidemiological studies. Journal of Affective Disorders, 135, 10–19. [PubMed]

  8. Baglioni, C., Spiegelhalder, K., Lombardo, C., & Riemann, D. (2010). Sleep and emotions: A focus on insomnia. Sleep Medicine Reviews, 14, 227– 238. 16 of 21 | KALMBACH ET AL. [PubMed]

  9. Baglioni, C., Spiegelhalder, K., Regen, W., Feige, B., Nissen, C., Lombardo, C., ... Riemann, D. (2014). Insomnia disorder is associated with increased amygdala reactivity to insomnia-related stimuli. Sleep, 37, 1907–1917. [PubMed]

  10. Baldwin, D. Jr, & Daugherty, S. R. (2004). Sleep deprivation and fatigue in residency training: Results of a national survey of first-and second-year residents. Sleep, 27, 217–223. [Research Gate]

  11. Basta, M., Chrousos, G. P., Vela-Bueno, A., & Vgontzas, A. N. (2007). Chronic insomnia and the stress system. Sleep Medicine Clinics, 2, 279–291. [NCBI]

  12. Bastien, C. H., & Morin, C. M. (2000). Familial incidence of insomnia. Journal of Sleep Research, 9, 49–54. [Wiley Online Library]

  13. Bastien, C. H., Vallieres, A., & Morin, C. M. (2004). Precipitating factors of insomnia. Behavioral Sleep Medicine, 2, 50–62. [PubMed]

  14. Bathgate, C. J., Edinger, J. D., & Krystal, A. D. (2017). Insomnia patients with objective short sleep duration have a blunted response to cognitive behavioral therapy for insomnia. Sleep, 40, [PubMed]

  15. Bathgate, C. J., Edinger, J. D., Wyatt, J. K., & Krystal, A. D. (2015). Objective but Not Subjective Short Sleep Duration Associated with Increased Risk for Hypertension in Individuals with Insomnia. Sleep, 39, 1037–1045. [NCBI]

  16. Beattie, L., Espie, C. A., Kyle, S. D., & Biello, S. M. (2015). How are normal sleeping controls selected? A systematic review of cross-sectional insomnia studies and a standardized method to select healthy controls for sleep research. Sleep Medicine, 16, 669–677. [PubMed]

  17. Benjamins, J. S., Migliorati, F., Dekker, K., , Wassing, R., Moens, S., Blanken, T. F., ... Van Someren, E. J. W. (2017). Insomnia heterogeneity: Characteristics to consider for data-driven multivariate subtyping. Sleep Medicine Reviews, 36, 71–81. [Science Direct]

  18. Blom, K., Tillgren, H. T., Wiklund, T., Danlycke, E., Forssen, M., S  oder- € strom, A., € ... Kaldo, V. (2015). Internet-vs. group-delivered cognitive behavior therapy for insomnia: A randomized controlled non-inferiority trial. Behaviour Research and Therapy, 70, 47–55. [PubMed]

  19. Bonnet, M., & Arand, D. (1998). Heart rate variability in insomniacs and matched normal sleepers. Psychosomatic Medicine, 60, 610–615. [PubMed]

  20. Bonnet, M. H., & Arand, D. L. (2003). Situational insomnia: Consistency, predictors, and outcomes. Sleep, 26, 1029–1036. [PubMed]

  21. Bonnet, M. H., & Arand, D. L. (2010). Hyperarousal and insomnia: State of the science. Sleep Medicine Reviews, 14, 9–15. [Science Direct]

  22. Borkovec, T. D. (1982). Insomnia. Journal of Consulting and Clinical Psychology, 50, 880–895. 

  23. Brotman, D. J., Golden, S. H., & Wittstein, I. S. (2007). The cardiovascular toll of stress. The Lancet, 370, 1089–1100. [PubMed]

  24. Brummett, B. H., Krystal, A. D., Ashley-Koch, A., Kuhn, C. M., Zuchner, € S., Siegler, I. C., ... Williams, R. B. (2007). Sleep quality varies as a function of 5-HTTLPR genotype and stress. Psychosomatic Medicine, 69, 621–624. [NCBI]

  25. Buckley, T. M., & Schatzberg, A. F. (2005). There are exemplary sleep disorders on the interactions of the hypothalamic-pituitary-adrenal (HPA) axis and sleep: normal HPA axis activity and circadian rhythm. The Journal of Clinical Endocrinology & Metabolism, 90, 3106–3114. [PubMed]

  26. Buysse, D. J., Germain, A., Hall, M., Monk, T. H., & Nofzinger, E. A. (2012). A neurobiological model of insomnia. Drug Discovery Today: Disease Models, 8, 129–137. [NCBI]

  27. Cano, G., Mochizuki, T., & Saper, C. B. (2008). Neural circuitry of stress-induced insomnia in rats. Journal of Neuroscience, 28, 10167– 10184. [PubMed]

  28. Charles, L. E., Burchfiel, C. M., Fekedulegn, D., Vila, B., Hartley, T. A., Slaven, J., ... Violanti, J. M. (2007). Shift work and sleep: The Buffalo Police health study. Policing: An International Journal of Police Strategies & Management, 30, 215–227. [Research Gate]

  29. Chen, I. Y., Jarrin, D. C., Ivers, H., & Morin, C. M. (2017). Investigating psychological and physiological responses to the Trier social stress test in young adults with insomnia: A preliminary study. Sleep Medicine, 40, 11–22. [Science Direct]

  30. Drake, C. L., & Roth, T. (2006). Predisposition in the evolution of insomnia: Evidence, potential mechanisms, and future directions. Sleep Medicine Clinics, 1, 333–349. [ResearchGate]

  31. Drake, C. L., Scofield, H., & Roth, T. (2008). Vulnerability to insomnia: The role of familial aggregation. Sleep Medicine, 9, 297–302. [NCBI]

  32. Zachariae, R., Lyby, M. S., & Ritterband, L. (2016). M. and O'Toole, M. S. Efficacy of internet-delivered cognitive-behavioral therapy for insomnia–A systematic review and meta-analysis of randomized controlled trials. Sleep Medicine Reviews, 30, 1–10. [PubMed]

  33. Zoccola, P. M., Dickerson, S. S., & Lam, S. (2009). Rumination predicts longer sleep onset latency after an acute psychosocial stressor. Psychosomatic Medicine, 71, 771–775. [PubMed]