Benefits of α-Bisabolol Adaptogen

in Adaptogens Research

What is Bisabolol?

Bisabolol, formerly called α-Bisabolol, also known as levomenol, is monocyclic sesquiterpene alcohol. It occurs naturally but is very rare. Bisabolol is a colorless oily liquid that is partially soluble in water and glycerin but is completely soluble in ethanol.  It is a component of the essential oil that is extracted from the German chamomile plant. Bisabolol has a weak but sweet, floral aroma and sometimes fruity scent with herbal undertones, which is the reason it is used in the manufacturing of fragrances. Bisabolol has some skin healing properties, making it a popular ingredient in producing cosmetics and personal care products for hundreds of years.  Bisabolol has a lot of benefits ranging from its anti-irritant and anti-inflammatory properties to its antimicrobial properties.

Origin of Bisabolol

Bisabolol can be gotten from the bark of the Candeia (Vanillosmopsis erythropappa) and German Chamomile (Matricaria chamomilla or Matricaria recutita) Brazil tree. These are the main universal sources of bisabolol, so some preventive measures are put up in Brazil to prevent the deforestation of their rainforests.

 Uses of Bisabolol

Bisabolol is a compound that is very beneficial to the body. It is therefore used in many regards because of the benefits it tends to provide for the body. The uses of bisabolol are treated below.

1. Bisabolol is used in producing cosmetics, health care, and hair care products such as lipsticks, eye cream, sunscreen, facial cleansers, moisturizers, lotions, and more.

2. Bisabolol has anti-irritant properties, so it is widely used to protect the skin from damage.

3. Bisabolol can be used to fight against bacteria and cancerous cells in the body.

4.  Bisabolol can be used to improve the appearance of any skin that is damaged by moisturizing the skin and helping it to restore elasticity. 

5. Bisabolol helps in the reduction of sunburns on the skin and prevents signs of aging.

6. It is used as an analgesic to reduce stress, thereby easing and relaxing the body.

7.  Bisabolol possesses a sweet floral scent, producing fragrance in perfumes and other personal care products.

Health Benefits of Bisabolol

Apart from the fact that bisabolol is very appreciated in the cosmetics industry, it has many other properties that are beneficial to the health and wellbeing of man. Some benefits of bisabolol are below:

1. Bisadolol can serve as an antioxidant

In 2016, a study was carried out whose result showcased that bisabolol can provide protective and positive effects for conditions arising in the kidney. The protective function was attributed to the antioxidant properties which the compound possesses. Therefore, researchers concluded that bisabolol could treat injuries that may occur in the kidney.

Bisabolol possesses antioxidant properties, giving it the ability to treat kidney injuries.

2. Bisabolol can be used as a pain reliever

A study was carried out in 2011 which suggested that bisabolol had analgesic outcomes because it reduced inflammation and pain. This study concluded that bisabolol has the potential to relieve pain.

Bisabolol has the potential to relieve pain due to its anti-inflammatory properties.

3. Bisabolol has anti-inflammatory properties that can help to reduce skin irritations

Bisabolol can help to reduce skin irritations because of the anti-irritant and anti-inflammatory properties that it possesses.

A study done in 2014 showed that bisabolol could reduce the production of inflammatory chemicals and cytokines. Bisabolol inhibits skin inflammation without leaving any side effects.

According to findings, bisabolol can be employed in the treatment of skin irritations because of the anti-irritant and anti-inflammatory properties that it possesses.

4. Bisabolol can be used in the treatment of bacterial and fungal infections

Bisabolol possesses antifungal and antibacterial properties, giving it the ability to combat fungal and bacterial infections such as Staphylococcus aureus and other common fungal infections. (Paulie t al., 2011). Some other researches also show the potency of bisabolol against two species of Candida (Merghache D; Boucherit-Otmani Z; Merghache S; Chikhi I; Selles C; Boucherit K; 2014).

Bisabolol possesses antifungal and antibacterial properties, which makes it beneficial in treating bacterial and fungal infections.

 5. Bisabolol is effective in the treatment of bacterial infections

In a study carried out recently, bisabolol was considered to have antimicrobial effects against oral bacteria. The results obtained proved that bisabolol is very useful in oral healthcare products (Forrer; Kulik; Filippi; Waltimo, 2013).

According to research, bisabolol is very effective in treating bacterial infections because of its antimicrobial properties.

6. Bisabolol helps to protect the digestive system from damage

A study was published in 2018, and the study showed that bisabolol possesses gastro-protective effects, which makes it capable of protecting the digestive system from getting damaged. Bisabolol was compared with diclofenac which always had gastric damage as a side effect. Bisabolol appeared to protect against gastric damages. It was therefore concluded that bisabolol and diclofenac can work together for reducing inflammation and potential side effects  (Ortiz MI; Cariño-Cortés R; Ponce-Monter HA; Castañeda-Hernández G; Chávez-Piña AE; 2018).

Bisabolol possesses gastro-protective effects, which help to protect the digestive system from damage.

7. Bisabolol helps to reduce anxiety

In 2017, a study was published in Naunyn-Schmiedeberg's Archives of Pharmacology, and it indicated that bisabolol tends to reduce anxiety according to several experiments carried out. The study's outcome was that bisabolol could help induce relaxation by impacting the brain with gamma-aminobutyric acid (GABA) receptors (Tabari, Tehrani, MAB; 2017).

Conclusion

Bisabolol is proven to have many beneficial properties to one’s health and wellbeing. Many items like skin-care and hair-care products are made with the use of this adaptogen. There are many ongoing studies to determine more benefits of this compound.

Footnotes

Bisabolol

https://en.m.wikipedia.org/wiki/Bisabolol

What is Bisabolol? | Honest

https://www.honest.com/blog/wellness/ingredients/what-is-bisabolol/16459.html

Trulieve | Everything You Need to Know About Bisabolol

https://www.trulieve.com/discover/blog/everything-you-need-to-know-about-bisabolol-and-its-benefits

Muñoz-Pérez, V., Ortiz, M., Ponce-Monter, H., Monter-Pérez, V., & Barragán-Ramírez, G. (2018, July). Anti-inflammatory and utero-relaxant effect of α-bisabolol on the pregnant human uterus. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019870/

Sampaio, T., Costa, M., Meneses, G., Arrieta, M., Filho, A., Morais, G., . . . Martins, A. (2016, November 11). Nephroprotective effects of (−)-α-bisabolol against ischemic-reperfusion acute kidney injury. https://www.sciencedirect.com/science/article/pii/S0944711316302124

MAB; T. (2017, October). Evidence for the involvement of the GABAergic, but not serotonergic transmission in the anxiolytic-like effect of bisabolol in the elevated mouse plus-maze. https://pubmed.ncbi.nlm.nih.gov/28730280/

Pauli, A., De Lucca, A., Schilcher, H., Sien, T., Bhatnagar, D., & Walsh, T. J. (2011, December). Fungicidal and Bactericidal Properties of Bisabolol and Dragosantol. https://www.tandfonline.com/doi/abs/10.1080/10412905.2011.9700457

Merghache D;Boucherit-Otmani Z;Merghache S;Chikhi I;Selles C;Boucherit K;. (2014). Chemical composition, antibacterial, antifungal, and antioxidant activities of Algerian Eryngium tricuspidatum L. essential oil. https://pubmed.ncbi.nlm.nih.gov/24559136/

Rocha NF;Rios ER;Carvalho AM;Cerqueira GS;Lopes Ade A;Leal LK;Dias ML;de Sousa DP;de Sousa FC;. (2011, December). Anti-nociceptive and anti-inflammatory activities of (-)-α-bisabolol in rodents. https://pubmed.ncbi.nlm.nih.gov/21870032/

E. Cavalieri, S., L. Costarelli, M., E. Darra, S., MS. Tallman, D., FR. Appelbaum, D., JE. Lancet, S., . . . E. Lugli, L. (2011, January 01). Pro-apoptotic activity of α-bisabolol in preclinical models of primary human acute leukemia cells. Retrieved November, from https://translational-medicine.biomedcentral.com/articles/10.1186/1479-5876-9-45

Ortiz MI;Cariño-Cortés R;Ponce-Monter HA;Castañeda-Hernández G;Chávez-Piña AE;, M. (2018). Pharmacological interaction of α-bisabolol and diclofenac on nociception, inflammation, and gastric integrity in rats. Retrieved November, from https://pubmed.ncbi.nlm.nih.gov/29243833/

Maurya AK;Singh M;Dubey V;Srivastava S;Luqman S;Bawankule DU;. (2014). α-(-)-bisabolol reduces pro-inflammatory cytokine production and ameliorates skin inflammation.  https://pubmed.ncbi.nlm.nih.gov/24894548/